Efficacy

A randomised controlled trial of prednisolone, 25 mg daily in a presumably mildly affected group (only 10 of 21 patients needed to take the study drug while on vacation) showed that it had an effect. PLE resolved more quickly (by a mean of 3-6 days (95% CI 0-6 to 6-1 days)) with prednisolone than with placebo, despite the fact that for this study patients were

Which form of prophylactic phototherapy -psoralen-UVA photochemotherapy or UVB monotherapy - should be prescribed for severely affected patients?

encouraged to continue sun exposure after they developed PLE.26

It is unclear whether moderately potent or potent topical steroids help to suppress established PLE, but potent topical steroids may be of value prophylactically if applied immediately after exposure.27

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