Efficacy

An RCT compared 0-05% tretinoin with fluocinonide in 33 patients with atrophic and erosive LP.35 The reduction of severity score was significantly higher with fluocinonide. An RCT compared topical ciclosporin three washes per day (1500 mg/day) with triamcinolone paste in 13 patients.36 No difference in efficacy was demonstrated. Another controlled trial compared oil-based ciclosporin solution, 50 mg three times daily, with aqueous 1% triamcinolone acetonide solution in 20 patients.37 No difference was observed.

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