Efficacy

No systematic review was found.

Topical bath PUVA versus UVB

A 6-week left-right design CCT of 13 patients showed that, though effective, topical bath PUVA was not better than UVB.28

Oral PUVA versus UVB

The only RCT we found, a 3-month study of 35 patients, showed an effect in favour of oral PUVA.29 In this study, only one hand was treated but in most patients the untreated hand also improved. A CCT comparing UVB used at home with PUVA at the clinic showed no comparative advantage.30

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