Cryotherapy versus placebo or no treatment

Two small RCTs21,22 involving 69 adults compared cryotherapy with either placebo cream21 or no treatment.22 The pooled data did not demonstrate a significant difference in cure rates: 35% v34%; OR 0-82 (CI 0-16-4-24). One trial21 had a very low cure rate for cryotherapy (1/11) and the other22 had a very high cure rate in its placebo group (8/20).

Cryotherapy versus SA

Two RCTs15,16 compared SA with cryotherapy in 320 adults and children. There was no significant difference in cure rates between the two treatments: 65% v 62%; OR 1-15 (CI

Length of freeze

Four RCTs23-26 compared aggressive and gentle cryotherapy in 592 adults and children; however, definitions of aggressive and gentle differed and some studies included refractory warts whereas others did not. Overall, cure was achieved in 52% with aggressive cryotherapy and 31% with gentle cryotherapy; OR 3-69 (CI

Interval between freezes

Three RCTs15,27,28 showed no significant difference in cure rates between 2- 3- and 4-week intervals. Cure was generally achieved more quickly with shorter treatment intervals.

Optimum number of freezes

Only one RCT29 examined this question in 115 adults and children not cured after 3 months of three-weekly cryotherapy and showed no benefit of prolonging cryotherapy for a further 3 months. Cure rates were 43% and 38% in the treated and non-treated groups, respectively (no data available to calculate OR).

Getting Rid Of Warts Forever

Getting Rid Of Warts Forever

All wart sufferers, this is the day to stop the shame. How I Got Rid Of My Warts Forever and How You Can Get Rid Of Warts Naturally In 3 Days. With No Blisters, No Scars, And No Pain Without medications or expensive procedures. All by applying a simple, very natural and unbelievable FREE substance that can be found in almost every household.

Get My Free Ebook

Post a comment