Efficacy

No systematic reviews were found.

Topical retinoid versus topical corticosteroids

In a symmetrical double-blind study, the efficacy of triamcinolone acetonide 0-1% cream was compared with the same cream containing, in addition, 0-25% retinoic acid.31 The study involved 18 subjects with different types of eczema (12 atopic dermatitis, 4 allergic contact dermatitis, 1 nummular eczema, 1 dyshidrosis); the palms and soles were involved in only five patients. The duration of treatment was planned for 2 weeks, with the option to extend treatment to 3 weeks. The same observer scored erythema, oedema, vesicles, crusts, excoriations, scales, lichenifications and pruritus separately on a scale of 0-5. No statistically significant difference between the treatments was observed.

Oral retinoids

In an open uncontrolled study, 15 patients with hyperkeratotic hand eczema were treated with etretinate 25-75 mg daily for 3-20 months.32 Pronounced improvement was reported but the clinical value was limited because of severe side-effects. Another open study using 9-c/s-retinioic acid for 1-5 months in 38 patients with refractory therapy-resistant chronic hand eczema showed very good response in 21 patients (55%), a good response in 13 patients (34%), a moderate response in 2 patients (5-5%) and no response in 2 patients (5-5%), as assessed by patient and doctor, and only mild side-effects.33

Curing Eczema Naturally

Curing Eczema Naturally

Do You Suffer From the Itching, Redness and Scaling of Chronic Eczema? If so you are not ALONE! It strikes men and women young and old! It is not just

Get My Free Ebook


Post a comment