Efficacy

No systematic review was found.

Emollient versus topical corticosteroids

One controlled trial indicated a beneficial effect of a chamomile-extract-containing cream over a cream with 0-25% hydrocortisone, but not in comparison with 0-75% fluocortin butylester cream.17 Uncontrolled studies noted a reduction in steroid use in patients treated with a moisturising cream and in patients treated with a protective foam.18,19

Versus each other

In one left-right RCT, using patient preference as outcome parameter, there was limited evidence in favour of Aquacare HP over Calmurid, both of which contained 10% urea.20 One controlled clinical trial (CCT) with a left-right design did not detect an advantage of a urea cream over an aqueous cream.22

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