Efficacy

We found no systematic reviews. We found one trial of 17 participants (16 consecutive women and one man) followed for 3 months.20 The trial compared the topical application of a 0-2% betamethasone 17-valerate cream with cream excipient (placebo). Randomisation was used to allocate the side of the face to which creams were applied. There was good improvement (subjectively defined by physician and participants) in eight people, eight of whom considered betamethasone to be better than placebo. Three considered they achieved moderate improvement with either betamethasone or placebo, and four people said they had no improvement at all. One person withdrew from the trial.

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