Finding the best evidence

Michael Bigby

The ability to find the best evidence to answer clinical questions is crucial for practising evidence-based medicine. Finding evidence requires access to electronic searching, searching skills and available resources. Methods for finding systematic reviews and evidence about diagnosis, therapy and harm have been well developed.1

Evidence about therapy is the easiest to find. The best sources for finding the best evidence about treatment include:

• The Cochrane Library

• Searching the Medline and Embase databases

• Secondary journals and books (for example ACP Journal Club, Evidence-based Medicine and Clinical Evidence)

• Primary journals

• The National Guideline Clearinghouse (

• Bandolier (

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