Expected side-effects include pain, pruritus, burning at the site of application, erythema, inflammation and erosions.41 Some authors suggest application of the medication 4 times daily to reduce the duration of treatment,84 while others advocate pulse therapy once or twice weekly to decrease the intensity of discomfort.85 Although compliance with the latter regimen is higher, cure rates may be lower.86 Lower-leg ulceration has been reported with 5% 5-FU cream,81 and allergic reaction to 5-FU has been reported in conjunction with iontophoretic therapy.79
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Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.