Implications for clinical practice

Ciclosporin may be useful to obtain short-term control, but cannot be recommended for maintenance therapy.

We identified six RCTs, all of which had a left-right design (i.e. the contralateral hand of each patient served as control). Two RCTs found no evidence that x rays were superior to conventional topical medication. None of the trials had a follow up time longer than 6 months; therefore there was no evidence that ionising radiation induced a longer remission period than conventional topical medication.

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