• The natural history of impetigo is not known.
• Few placebo-controlled studies have been done.
• Many different antibiotic treatments have been studied against each other, often in small studies showing no significant differences.
• There is no evidence supporting the value of disinfecting treatments.
• Macrolide and cephalosporine antibiotics are more effective than non-betalactamase-resistant pencillins.
• Topical antibiotics such as mupirocin and fusidic acid are equally effective as oral antibiotics such as erythromycin and have fewer side-effects.
• Resistance patterns in causative bacteria change over time and should be taken into account when choosing a therapy for impetigo.
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