• Few RCTs on systematic review of treatments for BP were identified.
• The available evidence is inadequate to allow confident recommendation of optimal treatment.
• A less aggressive approach to therapy with low doses of corticosteroids may be sufficient for disease control and appears to be associated with less morbidity and mortality.
• Tetracyclines and nicotinamide may be effective but larger trials are needed to compare this therapy with low-dose prednisolone.
• The benefits of azathioprine and plasma exchange are difficult to assess.
Additional chapters on Cicatrical pemphigoid and Epidermolysis bullosa acquisita by Maria Roest are published on the book website http://www. evidbasedderm.com.
Are antimicrobials useful?
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