Limitations of clinical research

As in other disciplines, the past few decades have seen an impressive increase in clinical research in dermatology. However, the upsurge of clinical research has not been paralleled by methodological refinements and the quality of randomised controlled trials (RCTs) in dermatology seems to fall well below the usually accepted standards. Innovative thinking is needed in dermatology in order that clinical research addresses the important issues and does not simply ape the scientific design.

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