Methods of search

Studies were identified using Medline (1966 to January 2001) and Embase (1988 to January 2001) databases, with search terms including "polymorphic/polymorphous light eruption AND treatment OR prognosis". Abstracts were read to determine which were likely to be relevant.

QUESTIONS

What is the prognosis for resolution of PLE for a severely affected patient living in a temperate country?

Follow up of 94 Finnish patients (by questionnaire, supplemented by repeat clinical assessments of a subgroup) up to a mean of 32 years after onset found 24% (95% confidence interval (CI) 16-34%) to have experienced resolution of their PLE, and 51% (CI 41-62%) to have milder PLE.11 A recent report suggested that those with negative provocation tests may be more likely to proceed to remission than those with positive provocation tests.21

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