Medline 1966 to 3rd August 2001, EmBase 1980 to 3rd August 2001, Cochrane Library 2001 issue 3, Psycinfo 1970 to 3rd August 2001 and LILACs were searched for the terms "melasma", "chloasma" or "mask of pregnancy" as text words and/or keywords if present in the database. Randomised controlled trials (RCTs) were searched for first, using a filter; the remaining abstracts from the search were then scanned to see if any RCTs had been missed using the search filter. References from identified papers were searched. The results of the search were appraised by at least two of the authors.
How effective are preventive interventions in high-risk populations?
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