Can chemoprevention interventions reduce the risk of cancer?
A multicentre double-blind randomised placebo-controlled trial of 1312 patients with a history of BCC or SCC of the skin and a mean follow up of 6-4 years showed that 200 micrograms of selenium (in brewer's yeast tablets) did not have a significant effect on the primary endpoint of the development of BCC or SCC of the skin.31
A case-control study found that a significant twofold increase in the risk of melanoma among current users of the contraceptive pill (relative risk (RR) 2-0, 95% CI 1-2, 3-4) compared with 10 or more years of use (RR 3-4, 95% CI 1-7, 7-0). Risk did not appear elevated among past oral contraceptive users, even among those with longer duration of use, and risk did not decline linearly with time since last use. Risk of premenopausal melanoma may be increased among those with longer duration of use, and further research is needed to determine whether low-dose oestrogen pills in particular are associated with an increase in risk and to describe possible interactions between oral contraceptive use and sun exposure or other risk factors for melanoma.32
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Complete Guide to Preventing Skin Cancer. We all know enough to fear the name, just as we do the words tumor and malignant. But apart from that, most of us know very little at all about cancer, especially skin cancer in itself. If I were to ask you to tell me about skin cancer right now, what would you say? Apart from the fact that its a cancer on the skin, that is.