This review of the literature showed that many drugs or physical treatments have been used in the treatment of LP, but comparative studies are rare. In almost all open studies, the reported efficacy in small groups of patients was based on

Are other topical treatments more effective than topical corticosteroids for treating oral LP?

Does photochemotherapy improve oral LP?

imprecise global evaluation scores and many studies lack precise inclusion criteria. It is impossible to compare the balance of benefit/harm of these treatments in each clinical form of LP.

Nevertheless, the studies contain enough preliminary data to encourage the planning of larger RCTs. These future RCTs must evaluate cutaneous LP, non-erosive oral and erosive oral LP separately, and use specific objective criteria in each clinical type of LP.

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