This is the main output of the Collaboration. It is the single best source of reliable evidence about the effects of healthcare interventions. It is updated quarterly and is distributed on an annual subscription basis on CD-ROM and via the internet. It includes several databases.
• The Cochrane Database of Systematic Reviews (CDSR) contains protocols and reviews prepared and maintained by Collaborative Review Groups. It includes a comments and criticisms system to enable users to improve the quality of Cochrane reviews.
• The Database of Abstracts of Reviews of Effectiveness (DARE) is assembled and maintained by the NHS Centre for Reviews and Dissemination in York, England. It contains critical assessments and structured abstracts of other systematic reviews, conforming to explicit quality criteria.
• The Cochrane Central Register of Controlled Trials (CENTRAL) contains bibliographic information on tens of thousands of controlled trials, including reports published in conference proceedings and many other sources not currently listed in other bibliographic databases.
• The Cochrane Database of Methodology Reviews (CDMR) summarises the empirical basis for decisions about methods for systematic reviews and evaluations of health care.
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