Crohns Disease

Crohn's disease consists of granulomatous inflammatory lesions with edema and ulcers and may occur in any part of the gastrointestinal tract from the mouth to the anus. In the small intestine, the ileum is preferentially affected. Endoscopic findings include a variety of ulcers, such as discontinuous or regional cobblestone appearance, longitudinal ulcers, aph-thoid ulcers, and irregular ulcers. In patients with long-standing disease, repeated fibrosis may result in intestinal stenosis. Histologically, formation of noncaseating epithelioid cell granulomas is characteristic (Fig. 10.4.1).

Ileal Ulcer Medicine
strating a longitudinal ulcer of the ileum

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