Hemangioma, a tumor consisting of proliferated blood vessels, occurs frequently in the skin but may develop in any part of the body, including the gastrointestinal tract. It has not been clearly determined whether hemangioma is a hamartoma, neoplasm, or deformity of existing blood vessels generated in response to chronic stimuli. Hemangioma may be found in the gastrointestinal tract of patients with congenital disorders, such as Osler-Weber-Rendu disease and Maffucci's syndrome.

A 41-year-old man with Maffucci's syndrome was diagnosed as having systemic multiple hemangioma, enchondroma, and chondrosarcoma in the head. Double-balloon endoscopy was performed because of recurrent gastrointestinal bleeding, and a hemangioma was found in the jejunum (Fig. 10.6.6). A small bowel series also showed multiple similarly protruding lesions.

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