Electron Microscopy

Randomly arranged fibrils, 10 to 12 nm, are present in extracellular sites in affected arterioles and arteries, mesangial areas, often infiltrating GBMs, and occasionally in the interstitium (Fig. 18.3).

Figure 18.2. Congo red stain disclosing the abnormal material to stain positively, diagnostic of amyloid.
Figure 18.3. The abnormal material in amyloid is composed of numerous fine fibrils seen on electron microscopy.
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