Acanthamoebic keratitis

Improper contact lens wear and care are the most important risk factors. The condition is easily confused with herpes keratitis and if not properly diagnosed and treated, blindness is a common outcome. Patients usually present with severe eye pain and photophobia. The classical finding is a ring infiltrate in the cornea and the symptoms are usually much greater than the signs. Since Acanthamoeba is a neurotrophic organism, the presence of enlarged and prominent corneal nerves is an important clue to this condition. Treatment is difficult and requires prolonged use of relatively toxic medications like neosporin, dibromopropamidine, propamidine, polyhexamethylene biguanide and chlorhexidine.

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