Early Rapid Repolarization

This phase describes a brief fall in membrane potential towards zero following the rapid rise in phase 0. This occurs due to the start of potassium flow out of the cell under the positive intracellular electrical gradient and chemical gradients. At the same time slow, L type, Ca2+ channels open, providing a prolonged influx of calcium ions which maintains the positive intracellular charge There is also movement intracellularly of chloride following sodium into the cell along the electrical gradient. This leads to an initial rapid repolarization of the cell membrane to just above 0 mV.

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Peripheral Neuropathy Natural Treatment Options

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