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within a small region of a larger right-handed B-DNA molecule, creating two junctions at the B-Z transition region.

Curved DNA. DNA containing tracts of (A)3-4. (T)3-4 (that is, runs of three or four bases of A in one strand and a similar run of T in the other) spaced at 10-base pair intervals can adopt a curved helix structure.

In summary, DNA can exist in a very stable, right-handed double helix, in which the genetic information is very stable. Certain DNA sequences can also adopt alternative conformations, some of which are important regulatory signals involved in the genetic expression or replication of the DNA. see also Chromosome, Eukaryotic; Chromosome, Prokaryotic; DNA Microarrays; Gene; Genome; Nucleotide; Sequencing DNA; Triplet Repeat Disease.

Richard R. Sinden

Bibliography

Sinden, Richard R. DNA Structure and Function. San Diego: Academic Press, 1994.

DNA Footprinting cleave split nucleotide the building block of RNA or DNA

enzyme a protein that controls a reaction in a cell

DNA footprinting is a technique for identifying exactly where a protein binds to DNA. Knowing where a protein binds to DNA often aids in understanding how gene expression is regulated. Consequently, DNA footprinting is often part of a larger study to determine how a particular gene is controlled.

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