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SELECTED LANDMARKS OF THE HUMAN GENOME

Cataracts

Opioid receptor Prostate cancer

Tremor, familial essential

Ovarian cancer

Serotonin receptors

Deafness, autosomal dominant

Retinitis pigmentosa Colon cancer

Limb-girdle muscular dystrophy, autosomal dominant

Emery-Dreifuss muscular dystrophy

Deafness, autosomal recessive

Holoprosencephaly

Lissencephaly

Liver cancer oncogene

Cardiomyopathy, familial hypertrophic

Micropenis

Diabetes mellitus, non-insulin- BRCA1 associated dependent protein (breast cancer)

Epilepsy

Fish-odor syndrome

Long QT syndrome

Thyrotropin-releasing hormone deficiency

Metastasis suppressor

Cardiomyopathy, dilated

Moyamoya disease Muscular dystrophy, limb-girdle, type IC Obesity, severe

Lung cancer, small-cell

Spinocerebellar ataxia

Myotonic dystrophy Dopamine receptor

Ataxia telangiectasia

Alzheimer's disease

Programmed cell death

Ovarian cancer

263 million bases

255 million bases

Hyperlipoproteinemia

Alopecia

Deafness, autosomal dominant universalis H Colorectal cancer

Myeloid leukemia

214 million bases

Hand-foot-uterus ■ Cerebral cavernous syndrome ■ malformations

Polydactyly

Colon cancer

Retinitis pigmentosa ACTH deficiency

Achromatopsia

Aldosteronism

Osteogenesis imperfecta

Taste receptors

Cystic fibrosis

Colorblindness, blue cone pigment

Burkitt lymphoma

Choreoacanthocytosis Brachydactyly, type B1

Muscular dystrophy, Fukuyama congenital

Esophageal cancer

Dystonia, torsion, autosomal dominant Tuberous sclerosis

Albinism, brown and rufous

Cyclin-dependent kinase inhibitor

Galactosemia

Friedreich ataxia

Pseudohermaphroditism, male, with gynecomastia

Nail-patella syndrome

171 million bases

155 million bases

145 million bases i

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