Ooocx

antigen a foreign substance that provokes an immune response plasmid a small ring of DNA found in many bacteria biolistic firing a microscopic pellet into a biological sample (from biological/ballistic)

Bibliography

Tang, D. C., M. Devit, and S. A. Johnston. "Genetic Immunization Is a Simple Method for Eliciting an Immune Response." Nature 356 (1992): 152-154.

Ulmer, Jeffrey B., John J. Donnelly, and Margaret A. Liu. "DNA Vaccines Promising: A New Approach to Inducing Protective Immunity." ASM News 62 (1996): 476-479.

Weiner, David B., and Ronald C. Kennedy. "Genetic Vaccines." Scientific American 281 (1999): 50-57.

Wolff, J. A., et al. "Direct Gene Transfer into Mouse Muscle in vivo." Science 247 (1990): 1465-1468.

Dominance See Inheritance Patterns

Down Syndrome trisomy presence of Down syndrome, also called trisomy 21, is the single most common genetic three, inistead °f two, cause of moderate mental retardation. It occurs in about one of every eight copies of a particular . « 11* 1*1 t* 1 1 1 • 1 r r -1

chromosome hundred live births. It is caused by the inheritance of an extra copy of chro mosome 21. The condition was named after an English physician, J. Langdon Down, who in 1866 published the first report describing patients with similar facial features and mental retardation. The chromosomal basis of Down syndrome was not determined until nearly a century later.

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