Internet Resources

Kinetochore Function. McGill University. < sld028.htm>.

Kinetochore Structure. University of Texas. < Supplements/kinetchr.htm>.


Molecular chaperones are proteins and protein complexes that bind to mis-polypeptide chain of folded or unfolded polypeptide chains and affect the subsequent folding amino acids processes of these chains. All proteins are created at the ribosome as straight chains of amino acids, but must be folded into a precise, three-dimensional shape (conformation) in order to perform their specific functions. The misfolded or unfolded polypeptide chains to which chaperones bind are said to be "non-native," meaning that they are not folded into their functional conformation. Chaperones are found in all types of cells and cellular compartments, and have a wide range of binding specificities and functional roles.

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