r Cancer is number 1 target for both biotech & pharmaceutical companies r Infectious disease & central nervous system disorders represent 2nd & 3rd highest targets, followed by cardiovascular and immune system disorders r By mid 2004, number of discovery/preclinical candidates has nearly tripled in all areas

Fig. 4.11. Current Discovery Focus - 2003/2004 (Adapted with permission from Figure in Lawrence S. Acumen J Sciences 2003;1(1): 22-23. Drug development by indication.)

Source: Discovery and Preclinical Pipelines - 2003; Lawrence. Acumen J. of Sciences 2003;1:23; Biopharm Insight

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