unmet medical needs being addressed (more provider, payer, and health system acceptance), early stage research projects that are sufficient in number and fit their eight research areas, novelty in mechanism of action and competitive edge for as many products as possible in the pipeline, and best in class potential for some candidates. Another approach in research pipelines at many companies is a business unit that is an exploratory area for the company. It does not really fit into their designated therapeutic areas but has some very interesting science in important therapeutic areas for patient need and market opportunity. This area later may become a major company research area, but the company is keeping their opportunities open on a small scale, and often it is done through research collaborations with small companies who are expert with the new technology or with a university laboratory [31].

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