Perirenal Extramedullary Hematopoiesis

Extramedullary hematopoiesis in myelofibrosis is widely distributed, involving organs such as the pleura, lungs,

Extramedullary HematopoiesisPerirenal Lymphoma

Fig. 8—184. Perirenal lymphoma.

Spectrum of findings illustrated in four different patients.

(a) Several discrete soft tissue nodules in the perirenal fat.

(b) Confluent lobulated perirenal masses are associated with parenchymal involvement on the right. Note plaquelike thickening of Gerota's fascia and the bridging septa.

(Reproduced from Bailey et al.252)

(c) Massive perirenal lymphomatous mass on the left with displacement of the kidney, contiguous with retroperitoneal adenopathy.

(Courtesy of S. S. Doda, M.D., Diwan Chand Aggarwal Imaging Research Centre, New Delhi, India.)

(d) Bilateral perirenal "rinds" (arrows). They are of lower attenuation than adjacent enhancing renal parenchyma. This patient is postsplenectomy for Hodgkin's lymphoma.

(Courtesy of Michiel Feldberg, M.D., University of Utrecht, The Netherlands.)

Fig. 8—184. Perirenal lymphoma.

Spectrum of findings illustrated in four different patients.

(a) Several discrete soft tissue nodules in the perirenal fat.

(b) Confluent lobulated perirenal masses are associated with parenchymal involvement on the right. Note plaquelike thickening of Gerota's fascia and the bridging septa.

(Reproduced from Bailey et al.252)

(c) Massive perirenal lymphomatous mass on the left with displacement of the kidney, contiguous with retroperitoneal adenopathy.

(Courtesy of S. S. Doda, M.D., Diwan Chand Aggarwal Imaging Research Centre, New Delhi, India.)

(d) Bilateral perirenal "rinds" (arrows). They are of lower attenuation than adjacent enhancing renal parenchyma. This patient is postsplenectomy for Hodgkin's lymphoma.

(Courtesy of Michiel Feldberg, M.D., University of Utrecht, The Netherlands.)

Fibrosis Perirrenal Unilateral

Fig. 8—185. Retroperitoneal fibrosis in perirenal space.

Mass (black arrows) around right kidney in perirenal space originates from fibrous mass (M) adjacent to aorta (AO). Behind the pancreas, a linear fibrosis extends along the remnant of the left anterior renal fascia (white arrows). C = renal cyst; GB = gallbladder; RL = right liver. (Courtesy of Michiel Feldberg, M.D., University of Utrecht, The Netherlands.)

gastrointestinal tract, breast, skin, dura matter, kidneys, and adrenal glands. The pathogenesis is not completely understood. Reversion of the liver and spleen to their fetal hemopoietic function after an unidentified stimulus has been proposed. More recently, extramedullary he-matopoiesis has been suggested to result from hemato-genous spread of multipotential stem cells, with consequent infiltration of organs and tissues. Perirenal localization is a rare finding (Fig. 8-186), and only a few

cases have been reported in the literature.

Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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