Lewis S. Nelson
Treatment Guidelines Fulminant Hepatic Failure
Special Considerations:, Multiple-Dose Acetaminophen „Ingestions ,,andTylenolExtended,Reli.ef Chapter, References
Acetaminophen (^-acetyl-p-aminophenol, or APAP) is the most popular over-the-counter analgesic used in the United States. As an ingredient found in a wide variety of prescription and over-the-counter remedies, acetaminophen is one of the most common toxic exposures reported to poison centers nationwide. Because of its ubiquitous presence, acetaminophen poisonings often occur because of the erroneous belief that this medication is benign or because the victim was unaware that it was an ingredient in the ingested preparation. According to the Toxic Exposure Surveillance System in 1996, acetaminophen accounted for 5 percent of all toxic exposures, but also accounted for 11 percent of reported fatalities.1
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