Achildren Uncomplicated

1. Amoxicillin (Amoxil) 80-90 mg/kg/day PO divided bid or tid [B] Easy dose: 40 mg/kg/dose PO bid OR 30 mg/kg/dose PO tid Maximum: 750 mg/dose bid OR 500 mg/dose tid

Available in suspensions of 125 mg and 250 mg/5 mL

2. TMP/SMX (Bactrim, Septra) 6-12 mg/kg/day TMP and 30-60 mg/kg/day SMX PO divided bid [C; D in 3rd trimester] Easy dose: 1 mL/kg/day PO divided bid = 8 mg/kg/day TMP and 40 mg/kg/day SMX

Maximum: 20 mL/dose

Suspension of TMP 40 mg and SMX 200 mg/5 mL

3. Erythromycin/sulfisoxazole (Pediazole) 50 mg/kg/day erythromycin and 150 mg/kg/day sulfa PO divided tid or qid [C; D in 3rd trimester] Easy dose: 1.25 mL/kg/day PO divided tid or qid

Maximum: 10 mL/dose

Suspension of erythromycin 200 mg and sulfisoxazole 600 mg/5 mL If severe or refractory:

1. Amoxicillin/clavulanate (Augmentin) 80-90 mg/kg/day as amoxicillin, PO, divided bid or tid [B] Easy dose: 40 mg/kg/dose as amoxicillin, PO bid OR 30 mg/kg/dose as amoxicillin, PO tid

Maximum dose: 750 mg/dose as amoxicillin, PO bid OR 500 mg/dose as amoxicillin, PO tid Available in suspensions of 125 mg and 250 mg amoxicillin/5 mL

2. Cefuroxime axetil (Ceftin) 20-30 mg/kg/day PO divided bid [B] Easy dose: 20 mg/kg/day = 10 mg/kg/dose PO bid Maximum: 250 mg/dose

Available in suspension of 125 mg/5 mL

3. Cefpodoxime (Vantin) 10 mg/kg/day PO in 1 dose [B] Maximum: 400 mg/dose

Available in suspensions of 50 mg and 100 mg/5 mL

4. Cefprozil (Cefzil) 15 mg/kg/dose PO bid [B] Maximum: 250 mg/dose

Available in suspensions of 125 mg or 250 mg/5 mL

5. Clarithromycin (Biaxin) 7.5 mg/kg/dose PO bid (for severe penicillin allergy) [C] Maximum: 500 mg/dose

Available in suspensions of 125 mg or 250 mg/5 mL

B. ADULTS, SINUSITIS Notes:

1. Many ENT consultants consider decongestants an equally important component of therapy, but this is not supported by the literature. Sprays:

a. 0.25% phenylephrine (Neo-Synephrine) nasal spray tid to qid for 3 days only [C]

b. Oxymetazoline 0.05% (Afrin) nasal spray bid for 3 days only [C]

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