The selection of antibiotics depends on the suspected bacteriology of the infection, the patient's compliance, potential drug toxicity, and cost. 12 In uncomplicated UTIs, E. coli is the offending microorganism in the vast majority of cases, and this and other typical coliform pathogens remain susceptible to a variety of agents: trimethoprim, co-trimoxazole, nitrofurantoin macrocrystals, and the fluoroquinolones ( Ta.b!e,.9.0.-2).
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