An unstable patient with anaphylaxis refractory to treatment should be admitted to the intensive care unit. All patients who receive epinephrine should be observed for a minimum of 6 h. If the patient remains symptom free during this time, he or she may be discharged home.2 Factors to consider in discharge planning include distance from medical care, whether the patient lives alone, significant comorbidity, age, past history of severe reaction, and the use of b-blocking agents. 6

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