Both arterial and venous thrombi may result in local vascular obstruction or distant embolization. Antithrombotic agents interfere with these processes by (1) preventing formation of the platelet-fibrin net (blocking thrombin activation or platelet function) or (2) accelerating clot breakdown (fibrinolysis). Antithrombotic agents are grouped by mechanism of action.2 Anticoagulants block synthesis and activation of clotting factors. Antiplatelet agents interfere with platelet activation or aggregation. Fibrinolytics (inaccurately referred to as thrombolytics) dissolve the fibrin component of thrombi.
Was this article helpful?
This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.