Airway control is best obtained through endotracheal intubation for airway protection, positive pressure ventilation (oxygenation), patency, and pulmonary toilet. Sedatives, which are frequently used to facilitate intubation, can exacerbate hypotension through arterial vasodilatation, venodilation, and myocardial suppression. Furthermore, positive pressure ventilation reduces preload and cardiac output. The combination of these interventions can lead to hemodynamic collapse. Volume resuscitation or application of vasoactive agents may be required prior to intubation.
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