Angiotensin Ii Receptor Antagonist

The antihypertensive medications of this relatively new class are reversible, competitive inhibitors of the angiotensin II receptor. Losartan, the first drug of this class to be approved, has no effect on ACE but is a selective blocker of the AT receptor found in vascular smooth muscle. Experience is limited with losartan, but adverse effects have been reported to be minimal. Toxicity includes hypotension and bradycardia. Supportive measures, including intravenous normal saline, adequate monitoring, and close observation is indicated for anyone who may have ingested an overdose of an angiotensin II receptor antagonist.

Reducing Blood Pressure Naturally

Reducing Blood Pressure Naturally

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