Angiotensin Ii Receptor Antagonist

The antihypertensive medications of this relatively new class are reversible, competitive inhibitors of the angiotensin II receptor. Losartan, the first drug of this class to be approved, has no effect on ACE but is a selective blocker of the AT receptor found in vascular smooth muscle. Experience is limited with losartan, but adverse effects have been reported to be minimal. Toxicity includes hypotension and bradycardia. Supportive measures, including intravenous normal saline, adequate monitoring, and close observation is indicated for anyone who may have ingested an overdose of an angiotensin II receptor antagonist.

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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