Anticholinergic Toxicity

Leslie R. Wolf

Pharmacologic Properties ClinicalPresentation treatment Jimsonweed

Chapter, References

Because of the frequent use of tricyclic antidepressants, phenothiazines, antihistamines, and antiparkinsonian drugs, anticholinergic toxicity is commonly seen in the emergency department. Anticholinergic medications are commonly prescribed for elderly patients, often resulting in drug-induced delirium. Many drugs have anticholinergic properties (Table 177-1) that may be mild at therapeutic doses but are life-threatening in overdose. 1 The use and abuse of some plants and mushrooms also may result in anticholinergic toxicity.

TABLE 177-1 Anticholinergic Substances

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