Biosynthetic Failure

Biosynthetic failure refers to the aspects of uremia from loss of the renal hormones 1,25 (OH) 3 vitamin D3 and erythropoietin. The kidneys are primarily responsible for the secretion of erythropoietin and 1-a-hydroxylase, which is necessary to produce the active form of vitamin D 3. In ESRD patients, levels of both these hormones are significantly depressed. Since 85 percent of erythropoietin is produced in the kidneys, ESRD patients have depressed levels, contributing to anemia. Vitamin D 3 deficiency results in decreased gastrointestinal (GI) calcium absorption, inducing secondary hyperparathyroidism, responsible for the development of renal bone disease.

Diet And Exercise Expertise

Diet And Exercise Expertise

Get All The Support And Guidance You Need To Be A Success At Dieting And Exercise. This Book Is One Of The Most Valuable Resources In The World When It Comes To Better Physical Personal Development Through Better Living.

Get My Free Ebook

Post a comment