The hemorrhagic tendency in patients with vWD is highly variable among patients with the same type of vWD, even among patients from the same family who have an identical genetic defect. Most characteristics are mild bleeding symptoms from mucocutaneous surfaces (such as epistaxis), easy bruising, bleeding after dental extractions, menorrhagia, and gastrointestinal bleeding. Patients with type III vWD have a severe bleeding diathesis with spontaneous hematomas and hemarthroses similar to patients with severe hemophilia.
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