Brucellosis

Infection with Brucella may be either of acute or insidious onset. Brucellosis is characterized by fever, night sweats, undue fatigue, anorexia, weight loss, headache, and arthralgias. The laboratory diagnosis may be made in several ways: (1) culture positive from a clinical specimen, (2) at least a fourfold increase in Brucella agglutination titers between the acute and convalescent phases in serum taken at least 2 weeks apart and studied in the same laboratory, or (3) positive immunofluorescence of Brucella in a clinical specimen.

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