Carbonic Anhydrase Inhibitors

The prototype for this subclass of diuretic is acetazolamide, which is a nonbacteriostatic sulfonamide whose adverse reactions include severe allergic reaction and Stevens-Johnson syndrome. The primary action of this class of diuretic is to inhibit carbonic anhydrase in the kidney to prevent the reversible reaction of carbon dioxide and water to form carbonic acid. This results in loss of bicarbonate ions in the urine, along with sodium, potassium, and water. Overdose with this class of medication can lead to volume depletion and electrolyte disturbances, as well as non-anion-gap metabolic acidosis. Treatment is directed at reversing volume depletion, monitoring electrolytes, and restoring normal pH balance.

Was this article helpful?

0 0
How To Get Rid Of Bed Bugs

How To Get Rid Of Bed Bugs

If you seriously want know how to get rid of bed bugs, then this may be the most important letter you'll ever read!... Discover How To Solve Your Dilemma In What You Thought To Be Your Dream Vacation And Easily Taking The First Step To Conquer The Bed Bugs Trauma You May Have At This Moment! It doesn't matter, if you have never have any ideas on how to getting rid of bed bugs and how to banish it quickly in the shortest time possible, then this golden guides will show you everything steps you need to take against bed bugs banishing!

Get My Free Ebook


Post a comment