Chapter References

1. Litovitz TL, Smilkstein M, Felberg L, et al: 1996 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med 15:447, 1997.

2. Roberts DW, Bucci TJ, Benson RW, et al: Immunohistochemical localization and quantification of the 3-(cystein-S- yl)-acetaminophen protein adduct in acetaminophen hepatotoxicity. Am J Pathol 138:350, 1991.

3. Lieh-Lai MW, Sarnaik AP, Newton JF, et al: Metabolism and pharmacokinetics of acetaminophen in a severely poisoned young child. J Pediatr 105:125, 1984.

4. Flanagan RJ, Mant TGK: Coma and metabolic acidosis early in severe acute paracetamol poisoning. Hum Toxicol 5:179, 1986.

5. Ashbourne JF, Olson KR, Khayam-Bashi H: Value of rapid screening for acetaminophen in all patients with intentional drug overdose. Ann Emerg Med 18:1035, 1989.

6. Rumack BH, Matthew H: Acetaminophen poisoning and toxicity. Pediatrics 55:871, 1975.

7. Prescott LF: Paracetamol overdosage. Drugs 25:290, 1983.

8. Smilkstein MJ, Knapp GL, Kulig KW, et al: Efficacy of oral ^-acetylcysteine in the treatment of acetaminophen overdose. N Engl J Med 319:1557, 1988.

9. Prescott LF: Treatment of severe acetaminophen poisoning with intravenous acetylcysteine. Arch Intern Med 141:386, 1981.

10. Smilkstein MJ, Bronstein AC, Linden C, et al: Acetaminophen overdose: A 48 hour intravenous N-acetylcysteine treatment protocol. Ann Emerg Med 30:1058, 1991.

11. Mann TG, Tempowski JH, Volons GN, et al: Adverse reactions to acetylcysteine and effect of overdose. BMJ 289:217, 1984.

12. Keays R, Harrison PM, Wendon JA, et al: Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: A prospective controlled trial. BMJ 303:1026, 1991.

13. Spiller HA, Krenzolak EP, Grande GA, et al: A prospective evaluation of the effect of activated charcoal before N-acetylcysteine in acetaminophen overdose. Ann Emerg Med 23:519, 1994.

14. Kobrinsky NL, Hartfield D, Horner H, et al: Treatment of advanced malignancies with high-dose acetaminophen and N-acetylcysteine rescue. Cancer Invest 14:202, 1996.

15. Riggs BS, Bronstein AC, Kulig K, et al: Acute acetaminophen overdose during pregnancy. Obstet Gynecol 74:247, 1989.

16. Harrison PM, Wendon JA, Gimson AES, et al: Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure. N Engl J Med 324:1852, 1991.

17. O'Grady JG, Alexander GJM, Hayllar KM, et al: Early indicators of prognosis in fulminant hepatic failure. Gastroenterology 87:439, 1988.

18. Temple AR, Mrazik TJ: More on extended-release acetaminophen. N Engl J Med 333:1508, 1995.

19. Graudins A, Aaron CK, Linden CH: Overdose of extended-release acetaminophen. N Engl J Med 333:196, 1995.

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