The risk of rabies and the management of postexposure prophylaxis in children have been reviewed. 26 32 In infants and children, the dose of rabies vaccine for preexposure and postexposure prophylaxis is the same as that recommended for adults (Table 1..4.1-.3). The dose of HRIG for postexposure prophylaxis is based on body weight. For small children with multiple bites, the calculated dosage of HRIG may be insufficient to infiltrate all wounds. However, sterile saline can be used to dilute the volume twofold or threefold to permit thorough infiltration. 26
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