Contrast-enhanced cranial CT is rarely indicated in the emergency setting. Abnormalities detected only on contrast-enhanced cranial CT, such as meningitis, some subacute infarcts, and small metastases, rarely change the immediate diagnostic workup and treatment and are more appropriately evaluated with magnetic resonance imaging (MRI). In the case of infarction, administration of a contrast agent may exacerbate the patient's clinical condition. Furthermore, intravenous contrast material may obscure intracranial hemorrhage, especially in the subarachnoid space.
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