Differential Diagnosis

Diseases that should be considered in the differential diagnosis of Crohn's disease ( Ta.b!ยง.ZZ-2) include lymphoma, ileocecal amebiasis, sarcoidosis, deep chronic mycotic infections involving the GI tract, gastrointestinal tuberculosis, Kaposi's sarcoma, Campylobacter enteritis and Yersinia ileocolitis. Fortunately, most of these are uncommon conditions and can be differentiated by appropriate laboratory tests. Yersinia ileocolitis and Campylobacter enteritis may cause chronic abdominal pain and diarrhea similar to Crohn's disease but can be diagnosed by appropriate stool cultures. Acute ileitis should not be confused with Crohn's disease. Young patients with acute ileitis usually recover without sequelae and should not undergo surgery. When Crohn's disease is confined to the colon, ischemic bowel disease (particularly in the elderly) and pseudomembranous enterocolitis as well as ulcerative colitis must be included in the differential diagnosis.

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