In acute toxicity, prognosis may be influenced favorably by the rapid institution of BAL therapy. Recovery from arsenical neuropathy appears to be related more to initial severity of symptoms than to institution of chelation therapy, although in those patients who do recover, BAL appears to significantly shorten the duration of illness. Often, neurologic recovery occurs slowly over months to years. Normalization of hematologic values can occur in the absence of any specific therapy. BAL has a variable effect on the dermatologic manifestations; hyperpigmentation is unresponsive to this therapy.
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