Most patients with HHNS require intensive care monitoring for the first 24 h. Patients requiring ongoing replacement of potassium should have continuous cardiac monitoring until those losses are replenished and serum potassium has stabilized.

Some patients may actually meet the criteria for HHNS, have mild symptoms, and have a negative evaluation for comorbidity. In cases when a reliable discharge plan can be arranged, outpatient treatment may be acceptable following appropriate emergency department care. If there is any doubt, the patient should be admitted.

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