Any patient with the serious signs and symptoms associated with ethylene glycol or methanol intoxication or a history of significant ingestion even in absence of symptoms should be admitted to an intensive care setting. Fomepizole or ethanol administration and dialysis should be continued until serum blood levels are zero and acidosis has resolved. Suicidal patients should receive a psychiatric evaluation when their condition improves and prior to discharge from any facility.

Patients seen at facilities unable to provide hemodialysis or intensive care should be transferred (if sufficiently stable) to institutions capable of providing such care. Because the symptoms of ethylene glycol and methanol intoxication may be delayed, patients who have ingested these substances should be admitted to the hospital for observation and laboratory testing even if they are asymptomatic initially.

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