Effects on Exercise

Exercise capacity, as measured by VO2 max, drops dramatically on ascent to altitude, approximately 10 percent for each 1000-m altitude gain above 1500 m. During acclimatization, submaximal endurance increases appreciably after 10 days, but V O2 max does not. The mechanism of this decrement might be lack of adequate oxygen supply to the muscle cells due to the low driving pressure for diffusion of oxygen from the capillary. Another theory suggests that the CNS limits muscle activity to preserve its own oxygenation.

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Sleep Apnea

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